Friday, December 17, 2010
7:51 AM | Posted by Shams Burki | Edit Post
The correct answer is A. Learn about anticancer drugs, high yield stuff for USMLE. Bleomycin can cause pneumonitis, which progresses to pulmonary fibrosis. Cough and shortness of breath are indications of the development of this complication. The pulmonary toxicity is usually age- and dose-related, although an allergic form of pneumonitis has been reported.
Cisplatin (chioice B) produces tinnitus, hearing loss,
Mithramycin (choice C) is associated with hemolytic
uremic syndrome, thrombocytopenia, hepatotoxicity and nephrotoxicity.
Calcium-channel blockers, such as verapamil (choice
D), cause headache, dizziness, and nausea. They may increase the extent of heart block and worsen congestive heart failure.
Vincristine (choice E) causes neuropathy rather than